Manufacturing Services



 

State-of-the-Art Facilities

Our cutting-edge facilities and broad technology experience means we can offer a full range of cGMP production strategies depending on your peptide’s structural complexity. Additionally, we have a broad array of synthesis, purification, isolation, and analytical equipment as well as support infrastructure to find an optimal solution for your immediate and long-term peptide needs.


Europe
Braine, Belgium
Solid-phase and liquid-phase technology

Kouřim, Czech Republic
Recombinant DNA technology

Visp, Switzerland
Solid-phase, liquid-phase and recombinant DNA technology

Asia
Nansha, China
Solid-phase and liquid-phase technology

Upstream & Downstream Equipment
Solid-Phase
− Synthesizers from 50mL to 1 600L
− Cleavage systems

Liquid-Phase
− Vessel sizes range from 10L to 2 800L
− Cyclization lines

Recombinant DNA Technology
− Microbial production in vessels from 15m3 to 75m3


Purification
  • Large-scale HPLC (15 to 60cm)
  • Mid- and Small-scale HPLC
  • Various packing material options
  • Up to 100 bar
  • Quality Control (IPC methods & HPLC)


Isolation / Filtration
  • Lab-scale lyophilization (freeze dryers)
  • Industrial-scale lyophilization (up to 200kg ice/day)
  • Lab- and pilot-scale spray drying
  • Centrifuges
  • Agitate and static plate filters
  • Filter-dryer
  • Extraction devices
  • Hydrogenators


Strategic Support Infrastructure
  • Streamlined (worldwide) sourcing
  • Raw materials in rail-tank-cars
  • Tank-farms
  • No open handling
  • Adequate warehousing
  • Recycling systems
  • Exhaust gas treatment
  • Waste disposal